The Malaria Transmission Cycle - Nithin, Flora, Julia

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Mission Statement:

Malaria is an infectious disease that is caused by the Plasmodium parasite. It is transmitted to humans by female Anopheles mosquitoes that are born in water. If the mosquito is born in contaminated water with the parasite, the parasite develops inside the mosquito until it bites a human, transmitting the parasite. Mosquitoes can also be infective if they had a previous bloodmeal from an person with malaria. By biting a person, an infected mosquito transmits the disease. Once inside the human, the parasite targets the humans red blood cells, causing them to become sick with symptoms such as shaking chills, high fevers, and headaches. These symptoms can develop into major impacts such as multi-organ failure for adults and severe anemia, respiratory distress, and cerebral malaria for children. Malaria may even lead to death if not treated. Malaria transmission is common in places with humid climates like Africa or South Asia. About half of the world's population lives in areas of risk. In the US, about 2,000 cases are diagnosed each year. In 2018, there were 228 million cases worldwide. The same year, 405,000 people died. This was an improvement from 2016, when there were 445,000 deaths worldwide. If modeled we could find weak points in the complex adaptive system of this disease and target those weak points to limit or even eradicate this disease across the world.

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